1. What is Iron Saturation?

Iron saturation measures the percentage of iron-binding sites on transferrin that are occupied by iron. It's an important indicator of iron status in the body and helps diagnose iron deficiency or iron overload conditions.

2. How Does the Calculator Work?

The calculator uses the iron saturation formula:

Where:

• \( Iron \) — Serum iron concentration in μg/dL
• \( Total\ Iron\ Binding\ Capacity \) — TIBC in μg/dL

Explanation: The formula calculates the percentage of transferrin binding sites that are saturated with iron, providing insight into the body's iron availability.

3. Importance of Iron Saturation Calculation

Details: Iron saturation is crucial for diagnosing iron-related disorders. Low saturation may indicate iron deficiency, while high saturation can suggest iron overload conditions like hemochromatosis.

4. Using the Calculator

Tips: Enter serum iron and total iron binding capacity values in μg/dL. Both values must be positive numbers for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is the normal range for iron saturation?
A: Normal iron saturation typically ranges from 20% to 50%, though reference ranges may vary slightly between laboratories.

Q2: What does low iron saturation indicate?
A: Low iron saturation (<20%) often indicates iron deficiency anemia or inadequate iron stores.

Q3: What does high iron saturation indicate?
A: High iron saturation (>50%) may suggest iron overload conditions such as hemochromatosis or excessive iron supplementation.

Q4: When should iron studies be performed?
A: Iron studies are typically ordered when anemia is suspected, or when monitoring iron therapy or iron overload conditions.

Q5: Are there any preparation requirements for iron tests?
A: Fasting for 8-12 hours is often recommended, as iron levels can fluctuate after meals. Morning blood draws are preferred.